Antiviral Pre-activated

Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children

AbstractChildren have reduced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rates and a substantially lower risk for developing severe coronavirus disease 2019 compared with adults. However, the molecular mechanisms underlying protection in younger age groups remain unknown. Here we characterize the single-cell transcriptional landscape in the upper airways of SARS-CoV-2-negative (nā€‰=ā€‰18) and age-matched SARS-CoV-2-positive…

Antiviral improve

Antiviral May Improve Hearing Loss in Congenital CMV

Infants with isolated sensorineural hearing loss as a result of congenital cytomegalovirus (cCMV) infection may benefit from treatment with valganciclovir, according to results from the CONCERT nonrandomized trial. Subjects were found through the Newborn Hearing Screening program, using dried blood spot screening to confirm cCMV Infection. As a result of 6 weeks of therapy, more…

Antiviral Response

Antiviral response: Eosinophils active in immediate defense during influenza A infection

Credit: CC0 Public Domain For the first time in published literature, Le Bonheur Children’s Hospital and University of Tennessee Health Science Center (UTHSC) researchers showed that a variety of white blood cells known as eosinophils modify the respiratory barrier during influenza A (IAV) infection, according to a recent paper in the journal Cells. This research…


Pfizer CEO Says Antiviral Pill To Treat Covid Could Be Ready By End Of The Year

Topline A pill that can be ingested orally at home to combat Covid-19 when illness is first detected could be available to the public by the end of 2021, Pfizer CEO Albert Bourla told CNBC on Tuesday, noting that the antiviral treatment is expected to be effective against variants of the virus. Pfizer announced late…